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I too have began 300mg Seroquel. I t does make me very tired and lasts into the following morning. I am also taking 1mg Ativan not to exceed 3, and 200mg Trazodone at night, Citalopram 40 mg and increasing, 50 mg Hydroxyzine, 6 times a day. I feel your pain as I have recently started with a doctor who wants to take away the Ativan. I also take 50mg Seroquel during day, Ativan is also my saving as it works like nothing else does or ever has. I have extreme anxiety attacks that cripple my ability to work or simply take care of things at home. He says that the Seroquel should help with the anxiety,"Right" I think you should go to a doctor who will work with you on what is going on with you. Who will know better than you? I would tell him you want to participate in you treatment and if he isn't willing then go someplace else. This illness is just to complicated to have some hard nose doctor making all the calls. Since most of them only see us 15-30 minutes a couple times a month. The medications and how you react to them is different with everyone, he needs to help you find yours with information on side effects and long term benefits,
Hope this helps,
Linda